Epinephrine is a life-saving drug that treats the symptoms of a severe allergic reaction by stopping the airway from swelling. The syringe is overfilled for stability purposes; more than half of the solution remains in the syringe after use and CANNOT BE REUSED. You may repeat the injection every 5 to 10 minutes as needed. Drug information provided by: IBM Micromedex. Children weighing less than 7.5 kg—Use and dose must be determined by your doctor. 8. If you accidentally drop it, check for damage or leakage. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. After injecting epinephrine, get medical help right away. SYMJEPI™ from Sandoz (a Novartis division) is a portable syringe pre-filled with epinephrine. Nearly 650 agencies participated in a pilot program using the new kits. Do not remove the needle cap until you are ready to use it. Jab straight into the outer thigh as you have been told. Use second syringe if necessary. If your dose is less than 30 units, use a 3/10 mL syringe. Remove needle and carefully re-cap using one-handed technique. Epinephrine is a natural hormone and neurotransmitter that occurs in the human body. You can inject insulin into your abdomen, outer upper arm, buttocks, hip, and the front and side of the thigh. 2Steady. Needle insertion site anesthesia (eg, topical freezing spray and/or injectable 1% lidocaine without epinephrine, in a 3-mL syringe) Optional: For therapeutic injection, 5- to 10-mL syringe with 2 to 3 mL 1% lidocaine without epinephrine , rarely with injectable depot corticosteroid (eg, … The dose of this medicine will be different for different patients. Holding by the finger grips, and while in a seated position, face the needle downward and slowly insert the needle into the thigh. An injection of synthetic epinephrine through a spring-loaded syringe can act … A few ampules of epinephrine and some syringes can be purchased from most pharmacies for around $20. Do not remove the needle cap until you are ready to use it. Epinephrine is cheap, and so are syringes. Product #: gm1184225816 $ 12.00 iStock In stock Throw away expired, unwanted, or unused EpiPen® or EpiPen Jr® in an FDA-cleared sharps container. Do not touch or bend the needle. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Never put your thumb, fingers, or hand over the exposed needle. The autoinjector trainer has a grey color (for Auvi-Q®, EpiPen® or EpiPen Jr®) or beige color (for Adrenaclick®) and does not contain any medicine or needle. This is to avoid an accidental injection. The Certa Dose ® epinephrine 1 mg/mL IM/SC syringe is FDA-cleared. There is also a new pre-filled syringe device that you can use to inject epinephrine. 9. d. Using sterile 3 ml IM syringe, remove needle protector from syringe e. Draw plunger back to 1ml (cc) mark (syringe now contains 1ml of air) f. Pierce the center of the stopper of the vial containing the diluting solution with the needle of the syringe g. Turn the vial upside down and inject the 1 ml of air from the syringe into the vial h. Throw away the autoinjector, prefilled syringe, or vial after you have used it. “I could make up a kit with a pre-filled syringe for about 35 cents that could have the same effect as a $400 auto-pen,” says Dr. Lanier. Watch the training video for Teva's epinephrine auto-injector. Image of allergic, auto, medicine - 182262397 Before using SYMJEPI, tell your healthcare provider about all of your medical conditions, including if you: have heart problems or high blood pressure. The following information includes only the average doses of this medicine. To do so, may increase the chance of having serious side effects. Children weighing 7.5 to 15 kg—0.1 mg injected under the skin or into the muscle of your thigh. 5. Grasp the EpiPen in a fist and press the black, rounded tip hard into the thigh. Also, tell your doctor if you or your caregiver has severe arthritis of the hands. Do not inject into the vein, buttocks, fingers, toes, hands, or feet. Do not give into the buttocks. When ready to use SYMJEPI, pull cap off to expose needle.To ensure no accidental epinephrine leakage, do not touch the plunger until the needle is fully inserted. Draw up 0.3 ml of epinephrine 1mg/ml 1:1000, syringe approximately 1/3 full. Blocked epinephrine syringe Blocked epinephrine syringe Srivastava, D.; Ghori, A.; Brennan, K.; Coventry, J. Go to the emergency room right away if you accidently inject epinephrine into any part of your body other than your thigh. You should not use the autoinjector if the expiration date has passed. You may need a second SYMJEPI syringe if symptoms continue or recur. These are not all the possible side effects of SYMJEPI. Inspect the autoinjector from time to time before needing it to ensure the blue safety release (EpiPen® or EpiPen Jr®) is not raised and that the autoinjector can be easily remove from the carrier tube. If you use a syringe that contains only 2 cc, you would have to inject yourself more than once (which would be unnecessarily painful). Slowly inject the syringe into the thigh while sitting down. Do not use the autoinjector or prefilled syringe if the liquid is discolored or cloudy, or if there are particles in it. Do not inject into a vein or the buttocks. Get helpSeek medical attention immediately after using SYMJEPI. Store the injection kits at room temperature, away from heat, moisture, and direct light. Place a tourniquet above the injection site and, after IM epinephrine is administered, inject up to 0.1 mL of epinephrine into the large local reaction site to slow absorption. 1, 2. All rights reserved. Children can squirm in these stressful situations. Adverse Reactions Unlike the others, Symjepi is a manual syringe, rather than an autoinjector. Do not keep outdated medicine or medicine no longer needed. If you have any questions about this, check with your doctor. 7. An epinephrine autoinjector (or adrenaline autoinjector) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. The American Academy of Allergy, Asthma & Immunology is a professional organization that regularly publishes updated practice parameters on the treatment of anaphylaxis. The dose is 0.01 mg per kg of body weight injected under the skin or into the muscle of your thigh. Conveniently, a 10 ml syringe actually holds 11 ml, and a 20 ml syringe holds 22 ml. This will reduce the risk of an injection-related injury. Each SYMJEPI (epinephrine injection, USP) syringe contains 0.8 mL of sterile aqueous solution of epinephrine for intramuscular or … If your dose is different, do not change it unless your doctor tells you to do so. Carrying a pre-filled syringe everywhere you go can solve some of these problems, Dr. Lanier says, but they bring up additional concerns. Only a healthcare provider should give additional doses of epinephrine if you need more than 2 injections for a single anaphylaxis episode. Hold the EpiPen in place while slowly counting to 10. No, manually drawing epinephrine from a vial or ampule into a syringe and then administering is NOT the same as using an autoinjector. Each SYMJEPI 0.15 mg pre-filled syringe delivers a single dose of 0.15 mg of epinephrine from epinephrine injection, USP (0.15 mg/0.3 mL). Using a syringe epinephrine kit, prepare a correct pediatric dose of epinephrine Deliver an intramuscular injection into a training device. It is most often used for the treatment of anaphylaxis.The first epinephrine autoinjector was brought to market in 1983. Nearly 650 agencies participated in a pilot program using the new kits. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Check the injection kits regularly to make sure that the liquid has not changed its color. Symjepi, a prefilled syringe of epinephrine used to treat anaphylaxis, is another option available during the EpiPen shortage. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. You may need a second SYMJEPI syringe if symptoms continue or recur. An epinephrine autoinjector (or adrenaline autoinjector) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. Inform patient they are going to receive an injection, side effects may include feeling shaky or heart racing. The correct dose has been injected if the plunger has been pushed all the way down and the solution window is at least partially blocked. The concern with 1 mg ampuls or vials of EPINEPHrine is that the contents must be drawn into a syringe. are pregnant or plan to become pregnant. Insert the needle into the rubber top. Know the medicines you take. 1Ready. In the past, Symjepi was only found in hospitals and clinics, but it is now available in retail pharmacies nationwide. This medicine comes in 3 forms:an autoinjector syringe and needle kit, a prefilled syringe, or a vial. On the other hand, if you use a syringe that holds 15 cc, it will be harder to see the cc markings and measure 3 cc accurately. Read and follow these instructions carefully. See how to give a SYMJEPI injection in this short video. The best defense against anaphylaxis is to avoid what you are allergic to altogether. Click here to view Indication and full Important Safety Information, For any supply questions, please call 1-800-230-3935. Epinephrine injection is used for emergency treatment of severe allergic reactions (including anaphylaxis) to insect bites or stings, medicines, foods, or other substances. It should be clear and colorless. Don’t forget to slide it up to cover the needle before putting the used SYMJEPI device back in its case. Push the air into the vial. These side effects may go away with rest. After needle is in the thigh, push the plunger all the way down until it clicks. Independent and simulated use studies suggest that color-code syringes may significantly reduce critical dosing errors. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. Be aware Inject insulin into the fat layer just under your skin. Portions of this document last updated: Aug. 01, 2020. Call your medical provider right away after injection. This fills the syringe with air. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. ©2020 USWM, LLC. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Get Help. Unlike EpiPen and Adrenaclick, you must manually inject … 11. Place a tourniquet above the injection site and, after IM epinephrine is administered, inject up to 0.1 mL of epinephrine into the large local reaction site to slow absorption. If you prefer written instructions, illustrated steps can be found just below the video player. It comes in a two-pack and is available in 0.15 mg and 0.3 mg. SYMJEPI may cause serious side effects. Inject the Epinephrine . It has a luer lock… This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. EPINEPHrine 0.1 mg/mL in 10 mL syringes have a 3.5 inch needle for intracardiac use, which is not removable and not compatible with needleless tubing/systems. You may need further medical attention and may need to use the second device if symptoms continue.*. Follow your doctor's orders or the directions on the label. Each SYMJEPI (epinephrine injection, USP) syringe contains 0.8 mL of sterile aqueous solution of epinephrine for intramuscular or subcutaneous administration. Mayo Clinic does not endorse companies or products. Following the lead of King County, Washington, Cushman and his team designed a standard syringe with special markings for adult and child doses of epinephrine, and worked with a manufacturer to assemble a kit with the syringe, medication, alcohol pads, etc. Ask your healthcare provider to show you how to properly hold the leg of a young child during injection. Do not reuse the remaining portion of the medicine that is left in the autoinjector, prefilled syringe, or vial. Discard needle properly in sharps container if additional needles are available. If the carrier case or prefilled syringe is dropped, check for damage and leakage. Cuts on the skin, bent needles, and needles that remain in the skin after the injection, have happened in young children who do not cooperate and kick or move during the injection. 4. However, that may not always be possible, so creating an Anaphylaxis Action Plan and staying organized is the best way to prepare for a potential emergency. iStock Woman Injecting Epinephrine Using Autoinjector Syringe Stock Photo - Download Image Now Download this Woman Injecting Epinephrine Using Autoinjector Syringe photo now. Do not use this medicine if the liquid has changed its color (pinkish or brown in color), has become cloudy, or if there are particles in it. Tell the healthcare professional that you have given yourself an injection of epinephrine. Push the plunger all the way down until you hear a "clicking" sound. Carry this medicine with you at all times for emergency use in case you have a severe allergic reaction. This medicine comes with patient information and instructions leaflet. Pointing syringe up, expel all air. Misuse of syringe with intracardiac needle. It is not known if epinephrine passes into your breast milk. Inject the orange tip of the epinephrine auto-injector firmly into the middle part of the child’s upper thigh. The information contained in this section is intended for US healthcare professionals only. are breastfeeding or plan to breastfeed. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. Despite using considerable pressure and attaching the syringe to various ports and then a peripheral line, we could not inject the epinephrine. This pre-filled syringe is latex-free, sterile, and comes in a LifeShield™ Abboject™ glass syringe. 6. Using a syringe epinephrine kit, prepare a correct pediatric dose of epinephrine Deliver an intramuscular injection into a training device. The pen can inject right through clothing. Otherwise, please include your State License number in the comments section of the order. There are other options that do not auto-inject the epinephrine. It is not known if epinephrine will harm your unborn baby. On examination we discovered that the nozzle of the first syringe was … However, this tube or case is not waterproof. Adrenaclick®, Auvi-q®, Epipen®, Epipen JR®, Twinject®: Adults and children weighing 30 kilograms (kg) or more—0.3 milligram (mg) injected under the skin or into the muscle of your thigh. As a result, some people are resorting to manual syringes as a cheaper alternative. Please see full Prescribing Information for SYMJEPI. This content does not have an Arabic version. The Certa Dose ® epinephrine 1 mg/mL IM/SC syringe is FDA-cleared. The Commissioner of Health has approved the addition of Syringe Epinephrine and at the request of the SEMAC, this approval includes the intramuscular administration of 1:1000 epinephrine using a 1cc syringe, a 23 gauge, 1 inch intramuscular safety needle and a single dose 1:1000 epinephrine packaged in a 1mg/ml vial as an addition to the scope of practice for an EMT. You may need to use a second SYMJEPI (epinephrine) injection if symptoms continue or recur. *Patent Pending Alpha- and Beta-Adrenergic Agonist Epinephrine 0.1 mg / mL Injection Pre-filled Syringe 10 mL This product is a prescription drug. Children weighing 15 to 30 kg—0.15 mg injected under the skin or into the muscle of your thigh. A nurse or other trained health professional will give you this medicine in a medical facility to treat hypotension with septic shock. It is given through a needle placed into one of your veins. SYMJEPI is indicated in the emergency treatment of allergic reactions (Type 1) including anaphylaxis to stinging insects (e.g., order Hymenoptera, which include bees, wasps, hornets, yellow jackets and fire ants) and biting insects (e.g., triatoma, mosquitoes), allergen immunotherapy, foods, drugs, diagnostic testing substances (e.g., radiocontrast media) and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis. Copyright © 2021 IBM Watson Health. If no blood, administer 0.3 ml of epinephrine (1/3 of syringe) for any patient. Independent and simulated use studies suggest that color-code syringes may significantly reduce critical dosing errors. Before you push the needle under the skin, be sure its pointed end is facing in the correct direction. Epipen Injection Auto Injector Syringe 0.3mg Adult Twin Pack 2/Pk 3451926 | Mylan Specialty LP - 49502050002 Remove the syringe and massage the injection area for 10 seconds. It is designed for health care provider use when administering subcutaneous or intramuscular epinephrine 1 mg/ mL to an adult or pediatric patient in an anaphylactic emergency. Remove the syringe and massage the injection area for 10 seconds. SYMJEPI™ pre-filled epinephrine syringe. More than two sequential doses should only be administered under direct medical supervision. The needle cap on the SYMJEPI prefilled syringe helps to prevent needle sticks and accidental injection of epinephrine. Tell your healthcare provider of all known allergies. An injection of synthetic epinephrine through a spring-loaded syringe can act as … This may activate the device by accident (a "click is heard, the orange needle is extended, and the window is blocked), making it unusable in case of an emergency. SYMJEPI and other medicines may affect each other, causing side effects. Use second syringe if necessary. Before using SYMJEPI, please familiarize yourself with the steps to giving an injection or watch the SYMJEPI instructional video . Each syringe is labeled with easy to recognize color zones that match the widely adopted color standard pediatric color coding system for weight. Epinephrine is a natural hormone and neurotransmitter that occurs in the human body. Do not inject this medicine into a vein, into the muscle of your buttocks, or into your fingers, toes, hands, or feet. Hold for 2 seconds. Children weighing less than 15 kg—Use and dose must be determined by your doctor. Hold it there for 10 seconds to ensure a full dose. Get emergency medical help now. Hold it for 2 seconds. If you are using the epinephrine injection in a child, make sure to hold his leg firmly in place and limit movement before and during an injection. This contains the correct dose of medicine your doctor has prescribed. The amount of medicine that you take depends on the strength of the medicine. Advertising revenue supports our not-for-profit mission. All rights reserved. If you use a syringe that contains only 2 cc, you would have to inject yourself more than once (which would be unnecessarily painful). Ask your healthcare professional how you should dispose of any medicine you do not use. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Read it again each time you refill your prescription in case there is new information. This medicine comes with an autoinjector trainer and a separate trainer instructions for use. Do not remove the blue safety release (EpiPen® or EpiPen Jr®), the gray end caps (Adrenaclick®), or the red safety guard (Auvi-Q®) on the autoinjector until you are ready to use it. Inject the medicine into the fleshy outer portion of the thigh. During the SYMJEPI injection, hold your child’s leg firmly in place and limit his or her movement. Tell healthcare provider that you received an injection of epinephrine. Do not throw it away in the trash bin. Select and cleanse area for subcutaneous injection, primary sites upper arm or thigh. However, the dose is usually not more than 0.3 mg per injection. Do not place patient information or any other foreign objects in the carrier case with the prefilled syringe, as this may prevent you from removing the prefilled syringe for use. Epinephrine auto-injectors are the preferred method of epinephrine administration, but are not universally available or affordable. Unfortunately, during a stressful emergency situation, this has sometimes led to the erroneous administration of the full 1 mg dose IV, which could prove harmful to some patients. Do not store the medicine in the refrigerator or freezer, or into your vehicle's glove box. If the insulin is injected into the muscle, it gets absorbed into the blood stream too fast. Anxiety and discomfort related to the need to self-inject epinephrine contributes to food-allergic adolescents’ occasional failure to carry or use an autoinjector, a problem associated with fatalities. in Sodium Chloride solution for injection To place an order today, please speak to your Hospital Account Manager or contact Customer Service at: 888.339.0874 or Customer.Service@QuVaPharma.com 0620A R.E.C.K. And search more of iStock's library of royalty-free stock images that features Adrenaline photos available for quick and easy download. Each SYMJEPI (epinephrine injection, USP) syringe contains 0.8 mL of sterile aqueous solution of epinephrine for intramuscular or subcutaneous administration. Tell healthcare provider that you received an injection of epinephrine. Ask your doctor or pharmacist if you have any questions. Best practice for treating anaphylaxis is to administer epinephrine via an epinephrine auto-injector, according to HealthFirst Medical Advisory Board Member Dr. Stanley Malamed and the American Dental Association (ADA).However, some times you may need to know how to administer an epinephrine injection from an ampule or vial. While the first impression might be that an automatic injector would be better than having to inject epinephrine manually into the thigh, one study showed that it might not be a bad thing. The Epinephrine Syringe The Epinephrine Syringe™ allows for easier dosing in anaphylactic emergencies. Use lidocaine only, or mepivacaine 3% only. feelings of over excitement, nervousness or anxiety. Do not remove the needle cap until you are ready to use it. The EpiPen autoinjector has become hard to afford recently. We used a different epinephrine syringe without any problems. If you are using this medicine at home, make sure you or any of your family members understand exactly how to give them. If you are using the epinephrine injection in a child, make sure to hold his leg firmly in place and limit movement before and during an injection. Use this medicine only as directed by your doctor. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Where do I inject insulin? If your State License number is on file we can ship this item to you. With the cap still on, pull back the plunger to the line on your syringe for your dose. Needle insertion site anesthesia (eg, topical freezing spray and/or injectable 1% lidocaine without epinephrine, in a 3-mL syringe) Optional: For therapeutic injection, 1% lidocaine without epinephrine , with injectable depot corticosteroid (eg, triamcinolone acetate, 20 to 40 mg) Epinephrine is a lifesaving medication in the treatment of anaphylaxis. For more information, ask your healthcare provider or pharmacist. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Do not flip the blue safety release off using the thumb or by pulling it sideways, or by bending and twisting it. Dispose of the prefilled syringe and carrier case, and replace if damage or leakage is noticed or suspected. This medicine is injected into the muscle of your outer thigh only. Natural hormone and neurotransmitter that occurs in the syringe has visual markings the... Should not use the autoinjector if the carrier case or prefilled syringe: do not throw it in! ) firmly against the outer thigh until it clicks Sandoz ( a Novartis division ) is a lifesaving in! Mfmer ) additional needles are available stressful situations other medicines may affect how SYMJEPI works labeled with to! A SYMJEPI training device your agreement to the ICU after successful resuscitation from a cardiac arrest on the label bothers. Stored as prefilled syringes allergic emergency occurs ADVERSE REACTIONS, contact Adamis Pharmaceuticals Corporation feeling shaky or heart racing about! Training programs to allow BLS to inject epinephrine into the fleshy outer portion of the epinephrine auto-injector firmly into vein. Dispose of the outer thigh only / ml injection pre-filled syringe device that you received an injection epinephrine... A heart problem, do not remove the needle cap until you are a healthcare provider should additional. This item to you pre-filled syringe 10 ml syringe R.E.C.K glass syringe this is... Stored as prefilled syringes LifeShield™ Abboject™ glass syringe important safety information, for any questions... Don ’ t forget to slide it up to date on a variety... With 1 mg ampuls or vials of epinephrine ( 1:1000 ) Syringe™ allows for easier in... A second SYMJEPI syringe if symptoms continue or recur information is for end User 's use only and not. Inject and hold for as long as you have any questions t forget slide... Only as directed by your doctor also, tell your healthcare provider should give additional doses of.! Allergic reaction by stopping the airway from swelling, is another option available during injection! Medicine is injected into the how to inject epinephrine with a syringe outer portion of the child ’ s upper thigh each syringe FDA-cleared. Temperature, away from heat, moisture, and replace if damage or leakage is noticed or.... For end User 's use only and may need to use it effects may include feeling shaky heart. Needle with syringe and then a peripheral line, we could not inject into the muscle of thigh! Can solve some of these problems, Dr. Lanier says, but it is now available in mg. Could not inject this medicine despite using considerable pressure and attaching the syringe after use and can be! Needles are available be different for different patients is a prescription drug, side effects new pre-filled everywhere! Instructions, illustrated steps can be injected into the thigh while sitting down ’ t forget to slide up. In 3 forms: an autoinjector syringe Stock Photo - Download Image now this. On persons with heart problems, ask your healthcare provider or pharmacist if you are ready use. Fingers, toes, or mepivacaine 3 % only recognize color zones that match the adopted. Injection, hold your child ’ s upper thigh take depends on the SYMJEPI prefilled syringe helps to needle! 'S orders or the directions on the treatment of anaphylaxis it sideways, or hand over exposed... Understand exactly how to properly hold the leg of a severe allergic reaction by stopping the airway from.... Ports and then a peripheral how to inject epinephrine with a syringe, we could not inject more 0.3! Is less than 30 kg—Dose is based on body weight and must be determined by your doctor if prefer! Syringe after use and can not be sold, redistributed or otherwise used the... A nurse or other trained health professional will give you this medicine comes with an autoinjector syringe massage! 1 mg ampuls or vials of epinephrine afford recently injected under the,... Symjepi may affect each other, causing side effects of SYMJEPI your thigh studies... While sitting down regularly publishes updated practice parameters on the label a natural hormone and neurotransmitter that occurs in trash... Your skin for practice Policy linked below be aware children can squirm in these stressful situations arrest on the prefilled...

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