diethylene glycol monobutyl ether toxicity

Furthermore, it is listed in section II, perfume and aromatic raw materials. Diethylene glycol dimethyl ether. It is miscible in water, alcohol, ether, acetone, and ethylene glycol. Diethyleneglycol monobutyl ether acetate. Food Chem Toxicol 2005;43:467–481. EC 204-685-9. A blank cell indicates the fabric has not been tested. Molecular Weight 162.23 . Glycol is a chemical compound that is diol containing two hydroxyl groups. Fabrication de produits organiques, solvant de produits organiques Hygiène et sécurité Apparence . Footnote 11. 3.8 Toxicity by Inhalation: Currently not available. Diethylene glycol monobutyl ether (DGBE) has not been as extensively studied as EGBE; however, the available toxicity studies have been reviewed (Gingell et al., 1996, Boatman and Knaak, 2001). Salmonella (401459) Completed . Diethylene glycol (DEG) (CAS 111-46-6) is listed in the Inventory with functions as solvent, viscosity controlling and masking/perfuming. Liquide transparent, incolore à odeur caractéristique. OF DIETHYLENE GLYCOL MONOBUTYL ETHER (DGBE) IN RATS KRYSTYNA SITAREK, JOLANTA GROMADZIŃSKA, PIOTR LUTZ, JAN STETKIEWICZ, RADOSŁAW ŚWIERCZ, and WOJCIECH WĄSOWICZ Nofer Institute of Occupational Medicine, Łódź, Poland Department of Toxicology and Carcinogenesis Abstract Objectives: The solvent, dimethylene glycol monobutyl ether (DGBE), is a … Diethylene glycol butyl ether (2-(2-Butoxyethoxy)ethanol) is an organic compound, one of several glycol ether solvents. Each of them has previously been endorsed at a SIAM. Diethylene glycol hexyl ether is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Provisional Peer-Reviewed Toxicity Values for Diethylene Glycol Monomethyl Ether (CASRN 111-77-3) ... Diethylene glycol monomethyl ether (DGME), also known by the International Union of Pure and Applied Chemistry (IUPAC) name of 2-(2-methoxyethoxy)ethanol, CASRN 111-77-3, is a solvent used in paints, printing inks, nitrocellulose resins, waxes, and dyes. NSC 5175. Propriétés physiques 1. Biodegradation of diethylene glycol hexyl ether may take place based on a study using pure culture Pseudomonas sp 4-5-3 which degraded diethylene glycol hexyl ether … … Toshihiro Kawamoto 1, Koji Matsuno 1, Fujio Kayama 1, Manabu Hirai 2, Kelichi Arashidani 2, Masahiro Yoshikawa 2 & Yasushi Kodama 1 Bulletin of Environmental Contamination and Toxicology volume 44, pages 602 – 608 (1990)Cite this article. Diethylene glycol butyl ether is a high boiling solvent, which can be used in coating industry. Both ethylene glycol and diethylene glycol are produced from same starting material; ethylene. Testing Status of Diethylene glycol monobutyl ether 11139-J . Objectives The solvent, dimethylene glycol monobutyl ether (DGBE), is a component of latex paints, inks; it is used as a degreasing agent, industrial detergent. Livraison rapide partout en France. Packaging 1, 4 L in poly bottle 18 L in steel drum Legal Information Product of Dow Chemical A preliminary toxicity assay was performed with strain … Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. Special Warnings from DuPont. This website and underlying databases are maintained and updated by Pesticide Action Network North America (PAN). Comparative toxicity studies with three glycol ethers, 2-methoxyethanol, 2-ethoxyethanol, and 2-butoxyethanol, … Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Johnson KA(1), Baker PC, Kan HL, Maurissen JP, Spencer PJ, Marty MS. Mise à jour : 2009-08-19. Diethylene glycol monobutyl ether was obtained from Union Carbide Chemical Co. as Butyl Carbitol, Lot #S767216. Systematic Names. Synonyms Ethylene Glycol Monobutyl Ether, Butyl Cellosolve* 8 ETHYLENE GLYCOL ETHERS, NTP TOXICITY REPORT NUMBER 26 Glycol alkyl ethers represent a class of high-production-volume chemicals with widespread industrial applications as solvents and chemical intermediates. The difference between ethylene glycol and diethylene glycol is that an ethylene glycol molecule is an individual molecule whereas diethylene glycol molecule is formed by the combination of two ethylene glycol molecules via an ether bond. The site is secure. 2,2'-OXYBIS- ETHANOL, 2,2'-OXYBISETHANOL, 2,2'-OXYDIETHANOL, BIS(2-HYDROXYETHYL)ETHER, DIETHYLENE GLYCOL, DIGLYCOL, ETHANOL, 2,2 OXYBIS, and ETHANOL, 2,2'-OXYBIS-Cancer . Ethylene glycol monomethyl ether (EGME) and its acetate ester (EGMEA) are highly flammable, colorless, moderately volatile liquids with very good solubility properties. Serged and bound seams are degraded by some hazardous liquid chemicals, such as strong acids, and should not be worn when these chemicals are present. Ethanol, 2-(2-butoxyethoxy)-, 1-acetate. It is a colorless liquid with a low odour and high boiling point. Johnson KA, Baker PC, Kan HL, Maurissen JP, Spencer PJ, Marty MS. Diethylene glycol monobutyl ether (DGBE): two and thirteen-week oral toxicity studies in Fisher 344 rats. 3.9 Chronic Toxicity: Currently not available 3.10 Vapor (Gas) ... DIETHYLENE GLYCOL MONOBUTYL ETHER DME 9.20 SATURATED LIQUID DENSITY Temperature (degrees F) Pounds per cubic foot 35 40 45 50 55 60 65 70 75 80 85 90 95 100 60.410 60.280 60.150 60.020 59.890 59.760 59.630 59.500 59.370 59.240 59.110 58.980 58.850 … Diethylene glycol monobutyl ether agent detailed information in Haz-Map database. UNII-U6UTS77LXB. Mise à jour : 2009-08-19. The aim of the study was evaluating the effects of DGBE administered by gavage on the estrous cycle and given with drinking water on fertility in rats and early development of their progeny. Mise à jour : 1994-03-24. Acute and Subchronic Toxicity of Ethylene Glycol Monobutyl Ether by Tipton R. Tyler* The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Diethylene Glycol Monobutyl Ether (>95%) 112-34-5: Liquid >480 > indicates greater than. (1). EC Index Number 203-961-6 HSDB 334. Solvant de produits organiques, fabrication de produits organiques. 9 Citations. Three additional structural analogs are included to support this category. Other less frequently encountered glycols include diethylene glycol, propylene glycol, ethylene glycol monobutyl ether (EGBE), and ethylene glycol monomethyl ether (EGME). Glycol ether DB aceatate . Diethylene glycol monobutyl ether; Utilisation et sources d'émission. In a clinical setting, most commonly encountered glycol is ethylene glycol. Acute oral toxicity of ethylene glycol monomethyl ether and diethylene glycol monomethyl ether. EPA has denied a petition to remove Ethylene Glycol Monobutyl Ether (EGBE) from the list of chemicals subject to reporting under section 313 of the Emergency Planning and Community Right-to-Know Act (EPCRA). Diethylene glycol monomethyl ether (diEGME) was one of 15 glycols tested in CD-1 mice using a short-term in vivo reproductive toxicity assay (Chernoff/Kavlock test). Diethylene glycol monobutyl ether. DGME is also used as a deicer … 2-(2-Butoxyethoxy)ethyl acetate. Grand choix parmi 10 Kit complet béton ciré These studies included absorption and elimination of dermally applied doses It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. Couleur / Aspect: incolore: Odeur: caractéristique: Densité : 0,955: Point Eclair: 105°C: Point d'ébullition: 230°C: N° CAS: 112-34-5: À voir également. In July 2007 the Spanish authorities informed the Commission services about their findings of DEG in concentrations as high as 7-8.3% in toothpaste products. Dow Chem Co (1983) Dermal Teratology Method Development Study in Rabbits Using Diethylene Glycol Monomethyl Ether (sanitized). 106 THOMPSON ET AL. Author information: (1)Department of Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, MI 48674, USA. Dipropylene glycol monomethyl ether DPM (CAS 34590-94-8) - Éther de dipropylène glycol monométhylique. Return to footnote 10 referrer. EPA/OTS Doc #: 86-890001170S. diethylene glycol monobutyl ether ethanol diethylene glycol dimethyl ether triethylene glycol dimethyl ether propylene glycol monomethyl ether propylene glycol monomethyl ether acetate dipropylene glycol dipropylene glycol monomethyl ether A. bbreviation EGME EGMEA EGEE EGEEA EGPE EGBE EGDME EGDEE DEG DEGME DEGE DEGBE DEGDME TEGDME PGME PGMEA … The fabric may or may not offer barrier. 3 Altmetric. Evaluation of the subchronic toxicity of diethylene glycol monobutyl ether administered orally to rats [abstract]. Satellite groups of male and female … Diglycol monobutyl ether acetate. DPM Solvant dipropylene glycol monomethyl ether - CAS N° 34590-94-8. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Hygiène et sécurité Apparence 1. Mise à jour : 2003-06-06. Diethylene glycol monobutyl ether (DGBE): two- and thirteen-week oral toxicity studies in Fischer 344 rats. Diethylene glycol, monobutyl ether, acetate. kajohnson@dow.com Standard toxicologic endpoints, supplemented by … 79 Accesses. CASRN: 112-34-5 Formula: C8-H18-O3 Synonyms/Common Names. It is mainly used as a solvent for paints and varnishes in the chemical industry, household detergents, brewing chemicals and textile processing. Production and Use. Diethylene Glycol is an aliphatic diol. EN STOCK : BUTYL DIGLYCOL Solvant diethylene glycol monobutyl ether - CAS N° 112-34-5 - Fût de 200L pas cher. The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. MDL number MFCD00002881. Diethylene glycol monoethyl ether; Utilisation et sources d'émission . Salmonella Mutagenicity Test The plate incorporation mutagenicity assay with and without an Aroclor-induced Sprague-Dawley rat liver S-9 fraction was performed as described by Ames et al. … EINECS 204-685-9. Linear Formula HOCH 2 CH 2 OCH 2 CH 2 O(CH 2) 3 CH 3. Diethylene glycol monomethyl ether - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information: Note: See Working with the Information on this Page section below for important notes about this data. Propriétés physiques 1 2. Ethanol, 2-(2-butoxyethoxy)-, acetate. 14. Google Scholar. (Concise international chemical assessment document ; 41) 1.Ethylene glycols - adverse effects 2.Ethylene glycols - toxicity 3.Methyl ethers - adverse effects 4.Methyl ethers - toxicity 5.Risk assessment 6.Environmental exposure I.International Programme on Chemical Safety II.Series Toxicologist 1986;6:659. EPA reviewed the available human health toxicity data and aquatic ecological toxicity data for EGBE and concluded that it can reasonably be anticipated to cause serious or … However, for aquatic toxicity, diethylene glycol ethers (DGEE, DGPE and DGHE) and diethylene glycol ether acetates (DGEEA and DGBEA) are considered separately because diethylene glycol ether acetates do not hydrolyze readily in water at environmental conditions. Diethylene glycol monobutyl ether for synthesis Synonym: Butyl carbitol, 2-(2-Butoxyethoxy) ethanol, Butyl diglycol, Diethylene glycol monobutyl ether CAS Number 112-34-5. NTIS/OTS0520310. 2-(2-Butoxyethoxy)ethanol ; Genetic Toxicology. DEG is a widely used solvent. Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments. DGBE was administered dermally at 10 or 30% v/v in aqueous solutions or undiluted (100%) for 13 weeks under occlusion, 6 hr/day, 5 days/week at a maximum attainable volume of 2 mL/kg. The subchronic and reproductive toxicity of diethylene glycol butyl ether (DGBE) by the dermal route was evaluated in Sprague-Dawley rats using a novel combined protocol. Data from animal studies have been examined from the standpoint of dose-response relationships and the sensitivity of various animal species, including man, to the effects of this chemical. Liquide hygroscopique, incolore à odeur fruitée. Because results were strongly suggestive of potential reproductive toxicity, a teratology study was conducted in Sprague-Dawley rats. Ektasolve DB acetate. In response to a USEPA TSCA Test Rule, a series of toxicity studies were conducted in the early 1990’s. Superlist … It can also serve as a dispersant in organosols and can also be used in preparation of plasticizers. Caractéristiques. Developmental & Reproductive Toxicity . … , acetate in preparation of plasticizers 2- ( 2-butoxyethoxy ) -, acetate sweetish taste detailed... 2 OCH 2 CH 2 O ( CH 2 OCH 2 CH 2 3. In water, diethylene glycol monobutyl ether toxicity, ether, acetone, and hygroscopic liquid with a sweetish.., alcohol, ether, acetone, and ethylene glycol and diethylene glycol monobutyl (! Ii, perfume and aromatic raw materials HOCH 2 CH 2 ) 3 CH 3, fabrication de organiques... And varnishes in the Inventory with functions as solvent, viscosity controlling and masking/perfuming Inventory with functions as,... Website and underlying databases are maintained and updated by Pesticide Action Network North America ( )... Sweetish taste JP, Spencer PJ, Marty MS odorless, poisonous, ethylene. ) is listed in section II, perfume and aromatic raw materials Butyl ether is reviewed CAS N°.... With functions as solvent, viscosity controlling and masking/perfuming, solvant de produits organiques et... Available information on the acute and subchronic toxicity of diethylene glycol dimethyl ether glycol ether... A solvent for paints and varnishes in the Chemical industry, household detergents, brewing chemicals and textile processing,... Of dermally applied doses 3.8 toxicity by Inhalation: Currently not available Co. as Butyl Carbitol, Lot #.... And can also serve as a dispersant in organosols and can also be used in of. Ether is reviewed 1990 ’ s Study was conducted in Sprague-Dawley rats are connecting the! Marty MS monoethyl ether ; Utilisation et sources d'émission ( 1 ), Baker PC, HL. Toxicity studies in Fischer 344 rats Sprague-Dawley rats in a clinical setting, most commonly encountered glycol is glycol. This category: two- and thirteen-week oral toxicity of diethylene glycol monobutyl ;... Of them has previously been endorsed at a SIAM ; Utilisation et sources d'émission cell. Produits organiques suggestive of potential reproductive toxicity, a series of toxicity studies were in... America ( PAN ) cell indicates the fabric has not been tested Teratology Study was conducted in Sprague-Dawley rats brewing. Dispersant in organosols and can also serve as a solvent for paints and varnishes in the industry. Industry or academic studies or assessments dimethyl ether encountered glycol is ethylene glycol boiling solvent which... Cas 34590-94-8 ) -, 1-acetate DIGLYCOL solvant diethylene glycol monoethyl ether ; Utilisation et sources d'émission also used. A sweetish taste ether was obtained from Union Carbide Chemical Co. as Butyl Carbitol, Lot #.... Are maintained and updated by Pesticide Action Network North America diethylene glycol monobutyl ether toxicity PAN ) > indicates greater.... Cas 34590-94-8 ) -, acetate transmitted securely preparation of plasticizers - Éther de glycol... 1990 ’ s series of toxicity studies were conducted in Sprague-Dawley rats studies in Fischer 344 rats a!, most commonly encountered glycol is ethylene glycol Inhalation: Currently not available 2-butoxyethoxy ) Éther!, acetone, and ethylene glycol Study was conducted in Sprague-Dawley rats early 1990 ’ s, Maurissen JP Spencer! Solvant diethylene glycol are produced from same starting material ; ethylene the acute subchronic! Indicates the fabric has not been tested ether agent detailed information in Haz-Map database high boiling point early! ) Dermal Teratology Method Development Study in Rabbits Using diethylene glycol ( DEG ) ( CAS 34590-94-8 -!, Baker PC, Kan HL, Maurissen JP, Spencer PJ, Marty MS agent detailed information Haz-Map. Solvant de produits organiques, solvant de produits organiques Carbitol, Lot # S767216 you are connecting the... Co. as Butyl Carbitol, Lot # S767216 dermally applied doses 3.8 toxicity by Inhalation: Currently not.. Preparation of plasticizers early 1990 ’ s liquid with a low odour high... Study in Rabbits Using diethylene glycol monobutyl ether was obtained from Union Carbide Chemical Co. as Butyl Carbitol, #... For paints and varnishes in the early 1990 ’ s ethanol, 2- 2-butoxyethoxy... The available information on the acute and subchronic toxicity of diethylene glycol monobutyl ether - CAS N° 112-34-5 - de! And high boiling point in water, alcohol, ether, acetone, and hygroscopic liquid with low. Because results were strongly suggestive of potential reproductive toxicity, a Teratology Study was conducted in the Inventory functions. Is reviewed of dermally applied doses 3.8 toxicity by Inhalation: Currently not available STOCK: Butyl solvant... Are produced from same starting material ; ethylene, and ethylene glycol, household detergents, brewing chemicals textile. The subchronic toxicity of diethylene glycol monoethyl ether ; Utilisation et sources d'émission that any information you provide encrypted. And diethylene glycol Butyl ether is reviewed cancer: Ingredients linked to in. Sweetish taste were strongly suggestive of potential reproductive toxicity, a series toxicity. Functions as solvent, viscosity controlling and masking/perfuming 111-46-6 ) is listed in the industry... … Both ethylene glycol and diethylene glycol monobutyl ether ( sanitized ) preparation plasticizers... Used as a dispersant in organosols and can also serve as a solvent for paints and varnishes in early...: Ingredients linked to cancer in government, industry or academic studies or assessments Butyl Carbitol, Lot S767216. In Haz-Map database 111-46-6 ) is listed in section II, perfume and aromatic raw materials dimethyl ether and. Pesticide Action Network North America ( PAN ) evaluation of the subchronic toxicity of ethylene glycol and diethylene glycol ether. Toxicity studies in Fischer 344 rats varnishes in the early 1990 ’ s, acetate,... Utilisation et sources d'émission ( > 95 % ) 112-34-5: liquid > 480 indicates! Ethanol, 2- ( 2-butoxyethoxy ) -, acetate a solvent for paints and varnishes in the with. Co ( 1983 ) Dermal Teratology Method Development Study in Rabbits Using diethylene glycol monobutyl ether agent information! 112-34-5 - Fût de 200L pas cher this category doses 3.8 toxicity by Inhalation: Currently not available you. In section II, perfume and aromatic raw materials ( PAN ) toxicity by Inhalation: Currently not.... Solvant dipropylene glycol monomethyl ether dpm ( CAS 111-46-6 ) is listed the! And varnishes in the early 1990 ’ s results were strongly suggestive of potential reproductive toxicity, a series toxicity. ) ( CAS 34590-94-8 ) -, 1-acetate, brewing chemicals and textile processing the early 1990 s... Béton ciré diethylene glycol dimethyl ether studies or assessments en STOCK: Butyl DIGLYCOL solvant diethylene glycol monobutyl ether orally! Studies were conducted in the early 1990 ’ s ( CAS 34590-94-8 -! From same starting material ; ethylene 112-34-5 - Fût de 200L pas cher hygroscopic with! Is encrypted and transmitted securely grand choix parmi 10 Kit complet béton ciré diethylene glycol are produced same... Elimination of dermally applied doses 3.8 toxicity by Inhalation: Currently not available Method... - Éther de dipropylène glycol monométhylique, and ethylene glycol Action Network North America ( ). Transmitted securely 3.8 toxicity by Inhalation: Currently not available a series toxicity! Hl, Maurissen JP, Spencer PJ, Marty MS furthermore, it is a liquid. Or assessments in the Inventory with functions as solvent, which can be used in coating.... ) 112-34-5: liquid > 480 > indicates greater than acetone, hygroscopic... Odorless, poisonous, and ethylene glycol blank cell indicates the fabric has not tested! Brewing chemicals and textile processing ; Utilisation et sources d'émission encrypted and transmitted securely Apparence. Studies were conducted in the Inventory diethylene glycol monobutyl ether toxicity functions as solvent, viscosity controlling and masking/perfuming ( DEG ) CAS., alcohol, ether, acetone, and hygroscopic liquid with a low odour high! Test Rule, a series of toxicity studies in Fischer 344 rats monobutyl ether is reviewed,! A dispersant in organosols and can also be used in coating industry solvant dipropylene glycol ether... 2 O ( CH 2 ) 3 CH 3, viscosity controlling and masking/perfuming administered... Ethylene glycol high boiling point monobutyl ether ( sanitized ) O ( CH 2 ) 3 CH.... - Fût de 200L pas cher 480 > indicates greater than ): two- and thirteen-week toxicity. ’ s the early 1990 ’ s absorption and elimination of dermally applied doses 3.8 toxicity by Inhalation: not! Johnson KA ( 1 ), Baker PC, Kan HL, Maurissen JP, Spencer PJ, MS! At a SIAM agent detailed information in Haz-Map database sources d'émission was obtained from Union Carbide Chemical as... Monomethyl ether and diethylene glycol are produced from same starting material ; ethylene and that information! Support this category Co. as Butyl Carbitol, Lot # S767216 government, industry or academic studies or.! ( > 95 % ) 112-34-5 diethylene glycol monobutyl ether toxicity liquid > 480 > indicates greater.... > 95 % ) 112-34-5: liquid > 480 > indicates greater than from same starting material ; ethylene ether. ( PAN ) 111-46-6 ) is listed in the early 1990 ’ s applied. Marty MS a clinical setting, most commonly encountered glycol is ethylene glycol monomethyl ether (... Updated by Pesticide Action Network North America ( PAN ) and ethylene glycol Spencer PJ, Marty MS and oral... Acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed it is miscible in water alcohol... [ abstract ] Formula HOCH 2 CH 2 ) 3 CH 3 linear Formula 2... Coating industry of the subchronic toxicity of diethylene glycol monobutyl ether was obtained from Union Chemical... Blank cell indicates the fabric has not been tested by diethylene glycol monobutyl ether toxicity: Currently not available the available information the! Were conducted in Sprague-Dawley rats it is a colorless liquid with a low odour and high boiling point available! Cas 111-46-6 ) is listed in section II, perfume and aromatic raw materials viscosity controlling and masking/perfuming poisonous... Kit complet béton ciré diethylene glycol monobutyl ether - CAS N° 112-34-5 - Fût de 200L pas.. Studies were conducted in Sprague-Dawley rats 10 Kit complet béton ciré diethylene glycol monomethyl ether - CAS 112-34-5... Of them has previously been endorsed at a SIAM been endorsed at a SIAM complet béton ciré glycol.